Kdm7a - lysine (K)-specific demethylase 7A Gene

Also Known as Jhdm1d; mKIAA1718; A630082K20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 338523

Summary

Enables histone H3-methyl-lysine-9 demethylase activity and histone H3-tri/di-methyl-lysine-27 demethylase activity. Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm7a Products (1)

mRNA Protein Name
NM_001033430.4 NP_001028602.2 lysine-specific demethylase 7A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone H3K27me2/H3K27me3 demethylase activity IMP
IMP: Inferred from mutant phenotype
20194436 MGI
enables histone H3K9 demethylase activity IMP
IMP: Inferred from mutant phenotype
20194436 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20194436 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase 7A

  • [histone H3]-dimethyl-L-lysine9 demethylase 7A

  • jmjC domain-containing histone demethylation protein 1D

  • jumonji C domain-containing histone demethylase 1 homolog D

  • lysine-specific demethylase 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-107573 KDM2/7-IN-1 Inhibitor 99.9% Unkown
HY-RS07224 KDM7A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19701 Kdm7a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26196 Kdm7a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdm7a NCBI NCBI:80853