country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

IGHG2 - immunoglobulin heavy constant gamma 2 (G2m marker) Gene

Species: Homo sapiens

Gene Type: other

Gene ID: 3501

About IGHG2

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,643,203-105,644,789 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 121 orthologues, 82 paralogues and is associated with 1 phenotype.

Summary

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to Other organism; and phagocytosis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16457820	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in extracellular space	IDA IDA: Inferred from direct assay	25645918	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IGHG2 Protein Structure

C1-set

0
100
200
300
326 a.a.

IGHG2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Cross	IGHG2	P01859	q28109_bovin	Bos taurus	Q28109	Biochemical	16457820
Cross	IGHG2	P01859	q28109_bovin	Bos taurus	Q28109	Competition Binding	16457820

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant IGHG2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72605	IgG2 Fc Protein, Human (V161M, S257A, HEK293)	P01859-1 (E99-K326, V161M, S257A)	≥ 95%, as determined by reducing SDS-PAGE.

IGHG2 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82451	Human IgG2 Antibody (YA2196)	WB, IHC-P, ICC/IF	Human

Related Diseases

Diseases	Alias
Immunoglobulin Kappa Light Chain Deficiency	Recurrent Infections Associated With Rare Immunoglobulin Isotypes Deficiency IGKCD Kappa Chain Deficiency Kappa Light Chain Deficiency Kappa-Chain Deficiency Igg Subclass Deficiency With Iga Subclass Deficiency Isolated Igg Subclass Deficiency Selective Igg Subclass Deficiency