1. Gene
  2. IGHG2 - immunoglobulin heavy constant gamma 2 (G2m marker) Gene

IGHG2 - immunoglobulin heavy constant gamma 2 (G2m marker) Gene

Homo sapiens
Gene ID: 3501 | Gene type: other

About IGHG2

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,643,203-105,644,789 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 121 orthologues, 82 paralogues and is associated with 1 phenotype.

Summary

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

IGHG2 Protein Structure

C1-set

C1-set: Immunoglobulin C1-set domain (17 - 92)

C1-set

C1-set: Immunoglobulin C1-set domain (126 - 212)

C1-set

C1-set: Immunoglobulin C1-set domain (232 - 314)

  • 0
  • 100
  • 200
  • 300
  • 326 a.a.

Recombinant IGHG2 Proteins

Cat. No. Product Name Accession Purity
HY-P72601 IgG2 Fc Protein, Human (223a.a, V161M, S257A, HEK293) P01859 (V104-K326) ≥95%
HY-P72605 IgG2 Fc Protein, Human (228a.a, V161M, S257A, HEK293) P01859 (E99-K326, V161M, S257A) ≥95%
HY-P73144 IgG2 Fc Protein, Human (229a.a, S257A, HEK293) P01859 (E99-K327, S257A) ≥95%

Related Diseases

Diseases Alias
Immunoglobulin Kappa Light Chain Deficiency

Recurrent Infections Associated With Rare Immunoglobulin Isotypes Deficiency

IGKCD

Kappa Chain Deficiency

Kappa Light Chain Deficiency

Kappa-Chain Deficiency

Igg Subclass Deficiency With Iga Subclass Deficiency

Isolated Igg Subclass Deficiency

Selective Igg Subclass Deficiency

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus IGHG2 NCBI