Plscr3 - phospholipid scramblase 3 Gene

Also Known as Pls3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360549

Summary

Enables calcium ion binding activity and phospholipid scramblase activity. Predicted to be involved in several processes, including cardiolipin biosynthetic process; plasma membrane phospholipid scrambling; and regulation of release of cytochrome c from mitochondria. Predicted to act upstream of or within cellular response to lipopolysaccharide; Cholesterol homeostasis; and glucose homeostasis. Located in mitochondrial inner membrane. Colocalizes with mitochondrion. Orthologous to human PLSCR3 (phospholipid scramblase 3). [provided by Alliance of Genome Resources, Apr 2022]

Plscr3 Products (1)

mRNA Protein Name
NM_001012139.2 NP_001012139.1 phospholipid scramblase 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
29171872 RGD
enables phospholipid scramblase activity IDA
IDA: Inferred from direct assay
29171872 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
29171872 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipid scramblase 3

  • PL scramblase 3

  • ca(2+)-dependent phospholipid scramblase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10742 PLSCR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plscr3 NCBI NCBI:57048