2. Gene
  3. Srgap2 - SLIT-ROBO Rho GTPase activating protein 2 Gene

Srgap2 - SLIT-ROBO Rho GTPase activating protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1566016

Gene ID: 360840 | Gene type: protein coding

About Srgap2

Summary

Predicted to enable GTPase activator activity; protein homodimerization activity; and small GTPase binding activity. Predicted to be involved in several processes, including negative regulation of neuron migration; plasma membrane bounded cell projection organization; and substrate adhesion-dependent cell spreading. Located in cytoplasm and nucleus. Orthologous to human SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Srgap2 Products(2)

mRNA Protein Name
NM_001134958.1 NP_001128430.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform 2
NM_001401376.1 NP_001388305.1 SLIT-ROBO Rho GTPase-activating protein 2 isoform 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17710530 RGD
located in nucleus IDA
IDA: Inferred from direct assay
17710530 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLIT-ROBO Rho GTPase-activating protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13763 SRGAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13764 SRGAP2C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13765 SRGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srgap2 NCBI NCBI:23380