Man2b1 - mannosidase, alpha, class 2B, member 1 Gene

Also Known as Manb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361378

Summary

Enables alpha-mannosidase activity and mannose binding activity. Predicted to be involved in cellular protein modification process. Predicted to act upstream of or within learning or memory and mannose metabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Orthologous to human MAN2B1 (mannosidase alpha class 2B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Man2b1 Products (1)

mRNA Protein Name
NM_199404.1 NP_955436.1 lysosomal alpha-mannosidase precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables D-mannose binding IDA
IDA: Inferred from direct assay
8702598 RGD
enables alpha-mannosidase activity IDA
IDA: Inferred from direct assay
8702598 RGD
enables alpha-mannosidase activity IMP
IMP: Inferred from mutant phenotype
8717430 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysosomal alpha-mannosidase

  • mannosidase 2, alpha B1

  • mannosidase, alpha B, lysosomal

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70185 Lysosomal α-mannosidase / Unkown
HY-RS08010 MAN2B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Man2b1 NCBI NCBI:4125