Rnls - renalase, FAD-dependent amine oxidase Gene

Also Known as RGD1309804

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361751

Summary

Predicted to enable several functions, including NADH binding activity; epinephrine binding activity; and Monoamine Oxidase activity. Involved in response to epinephrine; response to ischemia; and response to salt. Located in extracellular space. Biomarker of chronic kidney disease; congestive heart failure; glomerulosclerosis; and interstitial nephritis. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human RNLS (renalase, FAD dependent amine oxidase). [provided by Alliance of Genome Resources, Apr 2022]

Rnls Products (2)

mRNA Protein Name
NM_001014167.2 NP_001014189.1 renalase isoform 2 precursor
NM_001399688.1 NP_001386617.1 renalase isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in response to catecholamine IEP
IEP: Inferred from expression pattern
18299506 RGD
involved in response to epinephrine IEP
IEP: Inferred from expression pattern
18299506 RGD
involved in response to ischemia IEP
IEP: Inferred from expression pattern
21297953 RGD
involved in response to salt IDA
IDA: Inferred from direct assay
23314744 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
23314744 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

renalase

  • MAO-C

  • alpha-NAD(P)H oxidase/anomerase

  • monoamine oxidase-C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12101 RNLS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18635 Rnls Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25120 Rnls Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnls NCBI NCBI:55328