2. Gene
  3. SYNDIG1 - Syndig1 synapse differentiation inducing 1 Gene

SYNDIG1 - Syndig1 synapse differentiation inducing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as DSPC2; Tmem90b; RGD1310753

Gene ID: 362235 | Gene type: protein coding

About SYNDIG1

Summary

Predicted to enable glutamate receptor binding activity and protein homodimerization activity. Involved in positive regulation of synapse assembly and synaptic vesicle clustering. Located in cell body; dendrite; and excitatory synapse. Orthologous to human SYNDIG1 (synapse differentiation inducing 1). [provided by Alliance of Genome Resources, Apr 2022]

SYNDIG1 Products(1)

mRNA Protein Name
NM_001025020.1 NP_001020191.1 synapse differentiation-inducing gene protein 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
20152115 RGD
involved in regulation of postsynapse assembly EXP
EXP: Inferred from Experiment
20152115 RGD
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
20152115 RGD
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
20152115 RGD
involved in synaptic vesicle clustering IDA
IDA: Inferred from direct assay
20152115 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell body IDA
IDA: Inferred from direct assay
20152115 RGD
located in dendritic shaft IDA
IDA: Inferred from direct assay
20152115 RGD
located in dendritic spine IDA
IDA: Inferred from direct assay
20152115 RGD
located in excitatory synapse IDA
IDA: Inferred from direct assay
20152115 RGD
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
20152115 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20152115 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
20152115 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
20152115 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synapse differentiation-inducing gene protein 1

dispanin subfamily C member 2

transmembrane protein 90B

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14083 SYNDIG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14084 SYNDIG1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SYNDIG1 NCBI NCBI:79953