Agap3 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Gene

Also Known as Centg3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362300

Summary

Predicted to enable GTPase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to Reactive Oxygen Species and protein import into nucleus. Predicted to be located in cell periphery and cytoplasm. Predicted to be active in nucleus. Orthologous to human AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Agap3 Products (1)

mRNA Protein Name
NM_001398853.1 NP_001385782.1 arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
23904596 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
23904596 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23904596 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23904596 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
23904596 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

  • centaurin, gamma 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00439 AGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agap3 NCBI NCBI:116988