Rad18 - RAD18 E3 ubiquitin protein ligase Gene

Predicted to enable several functions, including Y-form DNA binding activity; identical protein binding activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in several processes, including positive regulation of chromosome segregation; postreplication repair; and protein monoubiquitination. Predicted to act upstream of or within several processes, including negative regulation of DNA recombination; protein autoubiquitination; and spermatogenesis. Predicted to be located in centrosome; chromosome; and nucleus. Predicted to be part of Rad6-Rad18 complex. Predicted to be active in nucleus. Orthologous to human RAD18 (RAD18 E3 ubiquitin protein Ligase). [provided by Alliance of Genome Resources, Apr 2022]