Sppl2b - signal peptide peptidase-like 2B Gene
Also Known as RGD1308556
Species: Rattus norvegicus
Summary
Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; and regulation of immune response. Predicted to be located in several cellular components, including cytoskeleton; endosome membrane; and nucleoplasm. Predicted to be active in Golgi-associated vesicle membrane and lysosomal membrane. Predicted to be integral component of cytoplasmic side of endoplasmic reticulum membrane and integral component of lumenal side of endoplasmic reticulum membrane. Orthologous to human SPPL2B (signal peptide peptidase like 2B). [provided by Alliance of Genome Resources, Apr 2022]
Sppl2b Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001014200.2 | NP_001014222.1 | signal peptide peptidase-like 2B isoform 2 precursor |
| NM_001401073.1 | NP_001388002.1 | signal peptide peptidase-like 2B isoform 1 precursor |
| NM_001401074.1 | NP_001388003.1 | signal peptide peptidase-like 2B isoform 3 precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
signal peptide peptidase-like 2B |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-111360 | SPL-707 | Inhibitor | 99.64% | Unkown |
| HY-RS13705 | SPPL2B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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