SYNCRIP - Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein Gene

Rattus norvegicus

Also known as Ab2-339; hnRNP Q

Gene ID: 363113 | Gene type: protein coding

About SYNCRIP

Summary

Enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Involved in circadian rhythm; negative regulation of mRNA modification; and positive regulation of translation. Located in several cellular components, including neuronal cell body; nucleus; and proximal dendrite. Orthologous to human SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

SYNCRIP Products(4)

mRNA	Protein	Name
NM_001047916.3	NP_001041381.1	heterogeneous nuclear ribonucleoprotein Q isoform 1
NM_001395649.1	NP_001382578.1	heterogeneous nuclear ribonucleoprotein Q isoform 2
NM_001395650.1	NP_001382579.1	heterogeneous nuclear ribonucleoprotein Q isoform 3
NM_001395651.1	NP_001382580.1	heterogeneous nuclear ribonucleoprotein Q isoform 4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables mRNA 3'-UTR binding	IDA IDA: Inferred from direct assay	15798208	RGD
enables mRNA 5'-UTR binding	IDA IDA: Inferred from direct assay	17403780	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in circadian rhythm	IEP IEP: Inferred from expression pattern	15798208	RGD
involved in negative regulation of mRNA modification	IMP IMP: Inferred from mutant phenotype	11134005	RGD
involved in positive regulation of translation	IMP IMP: Inferred from mutant phenotype	17403780	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	20131911	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	15475564	RGD
is active in postsynaptic density	IDA IDA: Inferred from direct assay	20131911	RGD
located in proximal dendrite	IDA IDA: Inferred from direct assay	15475564	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

heterogeneous nuclear ribonucleoprotein Q

hnRNP-Q

liver regeneration-related protein LRRG077

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14082	SYNCRIP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	SYNCRIP	NCBI	NCBI:10492

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