2. Gene
  3. Plxnb3 - plexin B3 Gene

Plxnb3 - plexin B3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1560615

Gene ID: 363517 | Gene type: protein coding

About Plxnb3

Summary

Predicted to enable several functions, including Rho GDP-dissociation inhibitor binding activity; cell-cell adhesion mediator activity; and semaphorin receptor activity. Involved in negative regulation of cell migration; negative regulation of lamellipodium assembly; and semaphorin-plexin signaling pathway. Predicted to be located in cell surface. Predicted to be part of semaphorin receptor complex. Predicted to be integral component of plasma membrane. Orthologous to human PLXNB3 (plexin B3). [provided by Alliance of Genome Resources, Apr 2022]

Plxnb3 Products(1)

mRNA Protein Name
NM_001135878.1 NP_001129350.1 plexin-B3 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of cell migration IMP
IMP: Inferred from mutant phenotype
20696765 RGD
involved in negative regulation of lamellipodium assembly IMP
IMP: Inferred from mutant phenotype
20696765 RGD
involved in semaphorin-plexin signaling pathway IMP
IMP: Inferred from mutant phenotype
20696765 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plexin-B3

protein Plxnb3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10754 PLXNB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plxnb3 NCBI NCBI:5365