Elavl1 - ELAV like RNA binding protein 1 Gene

Also Known as HuR; Hua

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363854

Summary

Enables mRNA 3'-UTR binding activity and protein kinase binding activity. Predicted to be involved in several processes, including protein homooligomerization; protein import into nucleus; and regulation of gene expression. Predicted to act upstream of or within positive regulation of translation. Located in cytoplasm and nucleus. Orthologous to human ELAVL1 (ELAV like RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Elavl1 Products (1)

mRNA Protein Name
NM_001108848.1 NP_001102318.1 ELAV-like protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
12234802 RGD
enables mRNA binding IDA
IDA: Inferred from direct assay
26682942 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18161049 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
19812253 RGD
Biological Process GO Annotation Evidence References Source
involved in mRNA destabilization IMP
IMP: Inferred from mutant phenotype
26682942 RGD
involved in positive regulation of superoxide anion generation IMP
IMP: Inferred from mutant phenotype
26682942 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
28350193 RGD
located in nucleus IDA
IDA: Inferred from direct assay
28350193 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ELAV-like protein 1

  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

  • ELAV like 1

  • hu-antigen R

  • mRNA-stabilizing factor HuR

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100685 MS-444 99.42% Unkown
HY-RS04294 ELAVL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18308 Elavl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24786 Elavl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elavl1 NCBI NCBI:1994