Ern2 - endoplasmic reticulum to nucleus signaling 2 Gene

Rattus norvegicus

Gene ID: 365363 | Gene type: protein coding

About Ern2

Summary

Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; apoptotic chromosome condensation; and positive regulation of JUN kinase activity. Predicted to act upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum quality control compartment. Predicted to be part of IRE1-TRAF2-ASK1 complex. Orthologous to human ERN2 (endoplasmic reticulum to nucleus signaling 2). [provided by Alliance of Genome Resources, Apr 2022]

Ern2 Products(1)

mRNA	Protein	Name
NM_001108919.1	NP_001102389.1	serine/threonine-protein kinase/endoribonuclease IRE2 precursor

Protein Preferred Names

Protein Names

serine/threonine-protein kinase/endoribonuclease IRE2

endoplasmic reticulum (ER) to nucleus signalling 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04510	ERN2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ern2	NCBI	NCBI:10595

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