Alkbh8 - alkB homolog 8, tRNA methyltransferase Gene

Predicted to enable several functions, including catalytic activity, acting on a tRNA; tRNA binding activity; and transition metal ion binding activity. Predicted to be involved in cellular response to DNA damage stimulus; tRNA methylation; and tRNA wobble uridine modification. Predicted to be located in cytosol and nuclear body. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ALKBH8 (alkB homolog 8, tRNA methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]