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  3. (S)-mchm5U

(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis.

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(S)-mchm5U Chemical Structure

(S)-mchm5U Chemical Structure

CAS No. : 89665-83-8

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1 mg USD 350 In-stock
5 mg USD 780 In-stock
10 mg USD 1250 In-stock
25 mg USD 2500 In-stock
50 mg USD 4000 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis[1].

Molecular Weight

332.26

Formula

C12H16N2O9

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C=C1[C@@H](C(OC)=O)O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)NC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (376.21 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0097 mL 15.0485 mL 30.0969 mL
5 mM 0.6019 mL 3.0097 mL 6.0194 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.0097 mL 15.0485 mL 30.0969 mL 75.2423 mL
5 mM 0.6019 mL 3.0097 mL 6.0194 mL 15.0485 mL
10 mM 0.3010 mL 1.5048 mL 3.0097 mL 7.5242 mL
15 mM 0.2006 mL 1.0032 mL 2.0065 mL 5.0162 mL
20 mM 0.1505 mL 0.7524 mL 1.5048 mL 3.7621 mL
25 mM 0.1204 mL 0.6019 mL 1.2039 mL 3.0097 mL
30 mM 0.1003 mL 0.5016 mL 1.0032 mL 2.5081 mL
40 mM 0.0752 mL 0.3762 mL 0.7524 mL 1.8811 mL
50 mM 0.0602 mL 0.3010 mL 0.6019 mL 1.5048 mL
60 mM 0.0502 mL 0.2508 mL 0.5016 mL 1.2540 mL
80 mM 0.0376 mL 0.1881 mL 0.3762 mL 0.9405 mL
100 mM 0.0301 mL 0.1505 mL 0.3010 mL 0.7524 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(S)-mchm5U Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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