(S)-mchm5U
Based on 1 publication(s) in Google Scholar
(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis.
For research use only. We do not sell to patients.
- Purity: 98.87%
- CAS No.: 89665-83-8
- Formula: C12H16N2O9
- Molecular Weight:332.26
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) (S)-mchm5U
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Biological Activity
Chemical Information
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CAS No. 89665-83-8
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Appearance Solid
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Molecular Weight 332.26
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Formula C12H16N2O9
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Color White to off-white
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SMILES
O=C(N(C=C1[C@@H](C(OC)=O)O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)NC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell
Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism. [Abstract]2025 Oct 30;188(22):6151-6169.e24. PMID: 40840445
Solvent & Solubility
H2O : 125 mg/mL (376.21 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.0097 mL | 15.0485 mL | 30.0969 mL | 75.2423 mL |
| 5 mM | 0.6019 mL | 3.0097 mL | 6.0194 mL | 15.0485 mL | |
| 10 mM | 0.3010 mL | 1.5048 mL | 3.0097 mL | 7.5242 mL | |
| 15 mM | 0.2006 mL | 1.0032 mL | 2.0065 mL | 5.0162 mL | |
| 20 mM | 0.1505 mL | 0.7524 mL | 1.5048 mL | 3.7621 mL | |
| 25 mM | 0.1204 mL | 0.6019 mL | 1.2039 mL | 3.0097 mL | |
| 30 mM | 0.1003 mL | 0.5016 mL | 1.0032 mL | 2.5081 mL | |
| 40 mM | 0.0752 mL | 0.3762 mL | 0.7524 mL | 1.8811 mL | |
| 50 mM | 0.0602 mL | 0.3010 mL | 0.6019 mL | 1.5048 mL | |
| 60 mM | 0.0502 mL | 0.2508 mL | 0.5016 mL | 1.2540 mL | |
| 80 mM | 0.0376 mL | 0.1881 mL | 0.3762 mL | 0.9405 mL | |
| 100 mM | 0.0301 mL | 0.1505 mL | 0.3010 mL | 0.7524 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.