SVBP - small vasohibin binding protein Gene

Homo sapiens

Also known as CCDC23; NEDAHM

Gene ID: 374969 | Gene type: protein coding

About SVBP

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:42,807,052-42,817,397 (from NCBI)

This gene has 3 transcripts (splice variants), 182 orthologues and is associated with 2 phenotypes. Ubiquitous expression in testis (RPKM 21.3), fat (RPKM 15.7) and 24 other tissues.

Summary

Enables microtubule binding activity. Involved in axon development; proteolysis; and regulation of metallopeptidase activity. Acts upstream of or within negative regulation of endothelial cell migration; negative regulation of protein ubiquitination; and protein secretion. Located in apical part of cell. [provided by Alliance of Genome Resources, Apr 2022]

SVBP Products(1)

mRNA	Protein	Name
NM_199342.4	NP_955374.1	small vasohibin-binding protein

Protein Preferred Names

Protein Names

small vasohibin-binding protein

coiled-coil domain containing 23

Related Diseases

Diseases

Alias

Neurodevelopmental Disorder With Ataxia, Hypotonia, And Microcephaly

NEDAHM

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Non-Specific Syndromic Intellectual Disability

Complex Neurodevelopmental Disorder

Hypotonia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14057	SVBP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SVBP	MGD	MGI:1916466
Bos taurus	SVBP	VGNC	VGNC:35497
Rattus norvegicus	SVBP	RGD	RGD:1311232
Macaca mulatta	SVBP	VGNC	VGNC:106503
Canis familiaris	SVBP	VGNC	VGNC:49865
Felis catus	SVBP	VGNC	VGNC:107670