Noto - notochord homeobox Gene

Also Known as tc; Flh; Not; MmNot

Species: Mus musculus

Gene Type: protein coding
Gene ID: 384452

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic organ development; motile cilium assembly; and regulation of cilium assembly. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesoderm; mesendoderm; primitive streak; and tail. Orthologous to human NOTO (notochord homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Noto Products (1)

mRNA Protein Name
NM_001007472.2 NP_001007473.1 homeobox protein notochord

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
17884984 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: Inferred from mutant phenotype
8155581 MGI
acts upstream of or within embryonic pattern specification IMP
IMP: Inferred from mutant phenotype
15550757 MGI
acts upstream of or within heart looping IMP
IMP: Inferred from mutant phenotype
17884984 MGI
acts upstream of or within motile cilium assembly IGI
IGI: Inferred from genetic interaction
22357932 MGI
acts upstream of or within notochord development IMP
IMP: Inferred from mutant phenotype
8155581 MGI
acts upstream of or within regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
17884984 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein notochord

  • Not homeodomain protein

  • floating head homolog

  • notochord homolog

  • truncate

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09453 NOTO Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Noto NCBI NCBI:344022