2. Gene
  3. Mir150 - microRNA 150 Gene

Mir150 - microRNA 150 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn150; mir-150; mmu-mir-150

Gene ID: 387168 | Gene type: ncRNA

About Mir150

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to decreased oxygen levels IEP
IEP: Inferred from expression pattern
19147652 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18762567 MGI
acts upstream of or within cellular response to phenylalanine IEP
IEP: Inferred from expression pattern
26822703 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: Inferred from mutant phenotype
17923094 MGI
acts upstream of or within immunoglobulin production IMP
IMP: Inferred from mutant phenotype
17927961 MGI
acts upstream of or within long-term synaptic potentiation IEP
IEP: Inferred from expression pattern
25858512 MGI
acts upstream of or within regulation of B cell differentiation IMP
IMP: Inferred from mutant phenotype
17927961 MGI
acts upstream of or within regulation of gene expression IDA
IDA: Inferred from direct assay
17927961 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
17927961 MGI
Cellular Component GO Annotation Evidence Reference Source
part of RISC complex IDA
IDA: Inferred from direct assay
23185045 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI00301 hsa-miR-150-5p inhibitor 99.71% Unkown
HY-R00301A hsa-miR-150-5p agomir 96.82% Unkown
HY-RI00301A hsa-miR-150-5p antagomir 98.26% Unkown
HY-R00301 hsa-miR-150-5p mimic 99.31% Unkown
HY-RI00300 hsa-miR-150-3p inhibitor 97.57% Unkown
HY-R00300 hsa-miR-150-3p mimic / Unkown
HY-R00300A hsa-miR-150-3p agomir / Unkown
HY-R02687 mmu-miR-150-3p mimic / Unkown
HY-R02687A mmu-miR-150-3p agomir / Unkown
HY-R04243 rno-miR-150-3p mimic / Unkown
HY-R04243A rno-miR-150-3p agomir / Unkown
HY-RI00300A hsa-miR-150-3p antagomir / Unkown
HY-RI02687 mmu-miR-150-3p inhibitor / Unkown
HY-RI02687A mmu-miR-150-3p antagomir / Unkown
HY-RI04243 rno-miR-150-3p inhibitor / Unkown
HY-RI04243A rno-miR-150-3p antagomir / Unkown
HY-R04627 mmu-miR-150-5p mimic / Unkown
HY-RI04611 mmu-miR-150-5p inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir150 NCBI NCBI:406942