2. Gene
  3. Mir15a - microRNA 15a Gene

Mir15a - microRNA 15a Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn15a; mir-15a; mmu-mir-15a

Gene ID: 387174 | Gene type: ncRNA

About Mir15a

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Wnt signaling pathway IDA
IDA: Inferred from direct assay
16682203 MGI
acts upstream of or within cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
20548288 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18762567 MGI
acts upstream of or within long-term synaptic potentiation IEP
IEP: Inferred from expression pattern
25858512 MGI
acts upstream of or within negative regulation of gene expression IDA
IDA: Inferred from direct assay
19416898 MGI
acts upstream of or within ossification IDA
IDA: Inferred from direct assay
25751060 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
24205035 MGI
acts upstream of or within response to oxygen levels IDA
IDA: Inferred from direct assay
19188439 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R00319 hsa-miR-15a-5p mimic 93.82% Unkown
HY-RI00318 hsa-miR-15a-3p inhibitor 96.31% Unkown
HY-RI00319 hsa-miR-15a-5p inhibitor 97.35% Unkown
HY-RI00319A hsa-miR-15a-5p antagomir 95.30% Unkown
HY-RI04246 rno-miR-15a-5p inhibitor 95.13% Unkown
HY-R00318 hsa-miR-15a-3p mimic / Unkown
HY-R00318A hsa-miR-15a-3p agomir / Unkown
HY-R00319A hsa-miR-15a-5p agomir / Unkown
HY-R02692 mmu-miR-15a-3p mimic / Unkown
HY-R02692A mmu-miR-15a-3p agomir / Unkown
HY-R04245 rno-miR-15a-3p mimic / Unkown
HY-R04245A rno-miR-15a-3p agomir / Unkown
HY-R04246 rno-miR-15a-5p mimic / Unkown
HY-R04246A rno-miR-15a-5p agomir / Unkown
HY-RI00318A hsa-miR-15a-3p antagomir / Unkown
HY-RI02692 mmu-miR-15a-3p inhibitor / Unkown
HY-RI02692A mmu-miR-15a-3p antagomir / Unkown
HY-RI04245 rno-miR-15a-3p inhibitor / Unkown
HY-RI04245A rno-miR-15a-3p antagomir / Unkown
HY-RI04246A rno-miR-15a-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir15a NCBI NCBI:406948