2. Gene
  3. Mir205 - microRNA 205 Gene

Mir205 - microRNA 205 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn205; mir-205; mmu-mir-205

Gene ID: 387201 | Gene type: ncRNA

About Mir205

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18762567 MGI
acts upstream of or within epithelial cell morphogenesis IDA
IDA: Inferred from direct assay
20103531 MGI
acts upstream of or within miRNA-mediated post-transcriptional gene silencing IMP
IMP: Inferred from mutant phenotype
23974039 MGI
acts upstream of or within negative regulation of gene expression IDA
IDA: Inferred from direct assay
21628588 MGI
acts upstream of or within negative regulation of osteoblast differentiation IDA
IDA: Inferred from direct assay
21628588 MGI
acts upstream of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
23974039 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
20103531 MGI
acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
23974039 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
23974039 MGI
acts upstream of or within regulation of cell size IDA
IDA: Inferred from direct assay
20103531 MGI
acts upstream of or within regulation of gene expression IDA
IDA: Inferred from direct assay
20103531 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
24205035 MGI
acts upstream of or within sensory perception of sound IEP
IEP: Inferred from expression pattern
23646144 MGI
acts upstream of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
23974039 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI00421 hsa-miR-205-5p inhibitor 96.81% Unkown
HY-R00421 hsa-miR-205-5p mimic 98.98% Unkown
HY-R00419 hsa-miR-205-3p mimic / Unkown
HY-RI00419 hsa-miR-205-3p inhibitor 97.21% Unkown
HY-R00419A hsa-miR-205-3p agomir / Unkown
HY-R00421A hsa-miR-205-5p agomir / Unkown
HY-R02817 mmu-miR-205-3p mimic / Unkown
HY-R02817A mmu-miR-205-3p agomir / Unkown
HY-R04292 rno-miR-205 mimic / Unkown
HY-R04292A rno-miR-205 agomir / Unkown
HY-RI00419A hsa-miR-205-3p antagomir / Unkown
HY-RI00421A hsa-miR-205-5p antagomir / Unkown
HY-RI02817 mmu-miR-205-3p inhibitor / Unkown
HY-RI02817A mmu-miR-205-3p antagomir / Unkown
HY-RI04292 rno-miR-205 inhibitor / Unkown
HY-RI04292A rno-miR-205 antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir205 NCBI NCBI:406988