2. Gene
  3. IDH2 - isocitrate dehydrogenase (NADP(+)) 2 Gene

IDH2 - isocitrate dehydrogenase (NADP(+)) 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 397603 | Gene type: protein coding

About IDH2

Primary_assembly 7: 55,651,609-55,675,554 reverse strand.Sscrofa11.1:CM000818.5

This gene has 3 transcripts (splice variants), 261 orthologues and 1 paralogue. Broad expression in heart (RPKM 46.1), psoas major muscle (RPKM 349.4) and 8 other tissues.

IDH2 Products(1)

mRNA Protein Name
NM_001164007.1 NP_001157479.1 isocitrate dehydrogenase [NADP], mitochondrial

IDH2 Protein Structure

PTZ00435

PTZ00435: PTZ00435 (38 - 450)

  • 0
  • 100
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  • 452 a.a.
Protein Preferred Names Protein Names

isocitrate dehydrogenase [NADP], mitochondrial

ICD-M

IDH

IDP

NADP(+)-specific ICDH

NADPH-specific isocitrate dehydrogenase

isocitrate dehydrogenase (NADP(+)) 2, mitochondrial

isocitrate dehydrogenase 2 (NADP+), mitochondrial

oxalosuccinate decarboxylase

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104042 Vorasidenib Inhibitor 99.76% Yes
HY-18690 Enasidenib Inhibitor 99.93% Yes
HY-18690A Enasidenib mesylate Inhibitor 99.68% Yes
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-131312 Crelosidenib Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15734 AGI-6780 Inhibitor 99.26% Unkown
HY-164542 TQ05310 Inhibitor / Unkown
HY-149359 IHMT-IDH1-053 Inhibitor / Unkown
HY-145743 CP-17 Inhibitor / Unkown
HY-120765 BRD2879 Inhibitor / Unkown
HY-131312A Crelosidenib gentisate Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IDH2 NCBI NCBI:3418