IDH2 - isocitrate dehydrogenase (NADP(+)) 2 Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 397603

About IDH2

Primary_assembly 7: 55,651,609-55,675,554 reverse strand.Sscrofa11.1:CM000818.5

This gene has 3 transcripts (splice variants), 261 orthologues and 1 paralogue. Broad expression in heart (RPKM 46.1), psoas major muscle (RPKM 349.4) and 8 other tissues.

IDH2 Products (1)

mRNA Protein Name
NM_001164007.1 NP_001157479.1 isocitrate dehydrogenase [NADP], mitochondrial

IDH2 Protein Structure

PTZ00435

PTZ00435: PTZ00435 (38 - 450)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 452 a.a.
Protein Preferred Names Protein Names

isocitrate dehydrogenase [NADP], mitochondrial

  • ICD-M

  • IDH

  • IDP

  • NADP(+)-specific ICDH

  • NADPH-specific isocitrate dehydrogenase

  • isocitrate dehydrogenase (NADP(+)) 2, mitochondrial

  • isocitrate dehydrogenase 2 (NADP+), mitochondrial

  • oxalosuccinate decarboxylase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104042 Vorasidenib Inhibitor 99.76% Yes
HY-18690 Enasidenib Inhibitor 99.93% Yes
HY-18690A Enasidenib mesylate Inhibitor 99.68% Yes

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-131312 Crelosidenib Inhibitor / Phase 1
HY-131312A Crelosidenib gentisate Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15734 AGI-6780 Inhibitor 99.26% Unkown
HY-164542 TQ05310 Inhibitor / Unkown
HY-149359 IHMT-IDH1-053 Inhibitor / Unkown
HY-145743 CP-17 Inhibitor / Unkown
HY-120765 BRD2879 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IDH2 NCBI NCBI:3418