MIR210 - microRNA 210 Gene
Also Known as MIRN210; mir-210
Species: Homo sapiens
About MIR210
This gene has 1 transcript (splice variant).
Summary
MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]
Related Diseases
| Diseases | Alias | |
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| Cardiovascular System Disease |
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| Head And Neck Cancer |
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| Heart Disease |
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| Myocardial Infarction |
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| Acute Promyelocytic Leukemia |
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| Ovarian Cancer |
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| Breast Cancer |
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| Miyoshi Muscular Dystrophy 1 |
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| Kidney Cancer |
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| Polymyositis |
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| Follicular Lymphoma |
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| Squamous Cell Carcinoma, Head And Neck |
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| Dermatomyositis |
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| Diffuse Large B-Cell Lymphoma |
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| Muscular Dystrophy, Duchenne Type |
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| Nemaline Myopathy |
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| Leukemia, Acute Lymphoblastic |
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| Alzheimer Disease, Familial, 1 |
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| Systemic Lupus Erythematosus |
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| Pancreatic Ductal Adenocarcinoma |
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| Pancreatic Cancer |
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| Glioblastoma |
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| Glioma |
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| Leukemia, Acute Myeloid |
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| Melanoma |
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| Lung Cancer |
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| Prostate Cancer |
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| Osteonecrosis |
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| Arteriosclerosis Obliterans |
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| Arteries, Anomalies Of |
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| Siderosis |
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| Larynx Cancer |
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| Endocrine Organ Benign Neoplasm |
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| Carbohydrate Metabolic Disorder |
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| Pre-Eclampsia |
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| Glucose Metabolism Disease |
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| Urinary System Disease |
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| Adrenal Gland Disease |
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| Castleman Disease |
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| Varicocele |
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| Chordoma |
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| Inherited Metabolic Disorder |
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| Bone Inflammation Disease |
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| Endocrine System Disease |
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| Immune System Disease |
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| Pancreas Disease |
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| Ischemia |
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| Autoimmune Disease Of Musculoskeletal System |
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| Cell Type Benign Neoplasm |
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| Acquired Metabolic Disease |
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| Autoimmune Disease Of Endocrine System |
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| Renal Cell Carcinoma, Nonpapillary |
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| Laryngeal Disease |
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| Endocrine Gland Cancer |
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| Ischemic Bone Disease |
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| Thoracic Cancer |
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| Respiratory System Cancer |
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| Placenta Disease |
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| Bone Sarcoma |
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| Overnutrition |
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| Respiratory System Disease |
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| Vascular Dementia |
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| Connective Tissue Cancer |
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| Pancreatic Cystadenoma |
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| Arteriosclerosis |
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| Uterine Anomalies |
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| Reproductive System Disease |
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| Central Nervous System Disease |
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| Female Reproductive System Disease |
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| Hypertension, Essential |
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| Cerebrovascular Disease |
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| Intestinal Disease |
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| Gastrointestinal System Disease |
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| Lymphatic System Disease |
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| Cervix Disease |
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| Bone Cancer |
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| Spinal Disease |
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| Cervical Cancer |
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| Pulmonary Hypertension |
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| Osteoporosis |
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| Retinal Disease |
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| Childhood Osteosarcoma |
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| Breast Disease |
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| Oral Cavity Cancer |
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| Gastrointestinal System Cancer |
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| Large Intestine Cancer |
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| Diabetes Mellitus |
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| Malignant Astrocytoma |
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| Tongue Squamous Cell Carcinoma |
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| Central Nervous System Cancer |
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| Upper Respiratory Tract Disease |
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| Bone Resorption Disease |
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| Bladder Disease |
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| Connective Tissue Disease |
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| Macular Degeneration, Age-Related, 1 |
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| Lymphatic System Cancer |
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| Sensory System Disease |
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| Bone Disease |
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| Male Reproductive System Disease |
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| Retinal Vascular Disease |
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| Male Reproductive Organ Cancer |
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| Pituitary Gland Disease |
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| Bone Remodeling Disease |
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| Colorectal Cancer |
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| Nervous System Disease |
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| Autoimmune Disease Of Central Nervous System |
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| Colonic Disease |
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| Hematologic Cancer |
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| Immune Deficiency Disease |
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| Eye Degenerative Disease |
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| Eye Disease |
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| Body Mass Index Quantitative Trait Locus 11 |
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| Lipoprotein Quantitative Trait Locus |
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| Type 2 Diabetes Mellitus |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | MIR210 | MGD | MGI:2676886 |
| Rattus norvegicus | MIR210 | RGD | RGD:2314887 |