CALHM6 - calcium homeostasis modulator family member 6 Gene

Also Known as INAM; FAM26F; C6orf187; dJ93H18.5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 441168

About CALHM6

Cytogenetic location: 6q22.1 Genomic coordinates (GRCh38): 6:116,461,375-116,463,771 (from NCBI)

This gene has 3 transcripts (splice variants), 133 orthologues and 5 paralogues. Biased expression in spleen (RPKM 28.1), appendix (RPKM 12.4) and 12 other tissues.

Summary

Predicted to enable cation channel activity. Predicted to be involved in cation transmembrane transport. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CALHM6 Products (2)

mRNA Protein Name
NM_001010919.3 NP_001010919.1 calcium homeostasis modulator protein 6 isoform 1
NM_001276460.2 NP_001263389.1 calcium homeostasis modulator protein 6 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CALHM6 Protein Structure

Ca_hom_mod

Ca_hom_mod: Calcium homeostasis modulator (1 - 247)

  • 0
  • 100
  • 200
  • 300
  • 315 a.a.
Protein Preferred Names Protein Names

calcium homeostasis modulator protein 6

  • IFN regulatory factor 3-dependent NK-activating molecule

CALHM6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CALHM6 Q5R3K3 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra
CALHM6 Q5R3K3 JAGN1 Homo sapiens Q8N5M9
Validated Y2H
32296183
Intra
CALHM6 Q5R3K3 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
Intra
CALHM6 Q5R3K3 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra
CALHM6 Q5R3K3 HSD17B13 Homo sapiens Q7Z5P4
Validated Y2H
32296183
Intra
CALHM6 Q5R3K3 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra
CALHM6 Q5R3K3 CBARP Homo sapiens Q8N350-4
Y2H Array
32296183
Intra
CALHM6 Q5R3K3 CBARP Homo sapiens Q8N350-4
Y2H Prey Pooling
32296183
Intra
CALHM6 Q5R3K3 CBARP Homo sapiens Q8N350-4
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01839 CALHM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CALHM6 VGNC VGNC:38671
Macaca mulatta CALHM6 VGNC VGNC:70684
Mus musculus CALHM6 MGD MGI:2443082
Bos taurus CALHM6 VGNC VGNC:26712
Rattus norvegicus CALHM6 RGD RGD:1304835
Others CALHM6 NCBI