Mib2 - MIB E3 ubiquitin protein ligase 2 Gene

Rattus norvegicus

Gene ID: 474147 | Gene type: protein coding

About Mib2

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and protein ubiquitination. Predicted to be located in early endosome. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in cytoplasm. Orthologous to human MIB2 (MIB E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mib2 Products(1)

mRNA	Protein	Name
NM_001005901.2	NP_001005901.2	E3 ubiquitin-protein ligase MIB2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of postsynaptic neurotransmitter receptor internalization	IDA IDA: Inferred from direct assay	17962190	RGD
involved in regulation protein catabolic process at postsynapse	IDA IDA: Inferred from direct assay	17962190	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	17962190	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	17962190	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase MIB2

RBSC-skeletrophin	RBSC-skeletrophin/dystrophin-like polypeptide
RING-type E3 ubiquitin transferase MIB2	mind bomb homolog 2
mindbomb E3 ubiquitin protein ligase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08423	MIB2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mib2	NCBI	NCBI:142678

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