Mib2 - MIB E3 ubiquitin protein ligase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 474147

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and protein ubiquitination. Predicted to be located in early endosome. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in cytoplasm. Orthologous to human MIB2 (MIB E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mib2 Products (1)

mRNA Protein Name
NM_001005901.2 NP_001005901.2 E3 ubiquitin-protein ligase MIB2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
17962190 RGD
involved in regulation protein catabolic process at postsynapse IDA
IDA: Inferred from direct assay
17962190 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17962190 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
17962190 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase MIB2

  • RBSC-skeletrophin

  • RBSC-skeletrophin/dystrophin-like polypeptide

  • RING-type E3 ubiquitin transferase MIB2

  • mind bomb homolog 2

  • mindbomb E3 ubiquitin protein ligase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08423 MIB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mib2 NCBI NCBI:142678