SCN8A - sodium voltage-gated channel alpha subunit 8 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 477604

About SCN8A

Primary_assembly 27: 3,172,854-3,345,743 reverse strand.ROS_Cfam_1.0:CM025126.1

This gene has 4 transcripts (splice variants), 276 orthologues, 27 paralogues and is associated with 1 phenotype.

SCN8A Products (5)

mRNA Protein Name
XM_038438135.1 XP_038294063.1 sodium channel protein type 8 subunit alpha isoform X1
XM_038438134.1 XP_038294062.1 sodium channel protein type 8 subunit alpha isoform X1
XM_038438133.1 XP_038294061.1 sodium channel protein type 8 subunit alpha isoform X1
XM_038438137.1 XP_038294065.1 sodium channel protein type 8 subunit alpha isoform X3
XM_038438136.1 XP_038294064.1 sodium channel protein type 8 subunit alpha isoform X2

SCN8A Protein Structure

Ion_trans

Ion_trans: pfam00520 (130 - 288)

Na_trans_cytopl

Na_trans_cytopl: pfam11933 (581 - 737)

Ion_trans

Ion_trans: pfam00520 (787 - 1000)

Na_trans_assoc

Na_trans_assoc: pfam06512 (1026 - 1227)

Ion_trans

Ion_trans: pfam00520 (1232 - 1508)

Na_channel_gate

Na_channel_gate: cd13433 (1500 - 1552)

Ion_trans

Ion_trans: pfam00520 (1557 - 1811)

GPHH

GPHH: cl25190 (1823 - 1870)

IQ

IQ: smart00015 (1929 - 1950)

  • 0
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  • 1600
  • 2016 a.a.
Protein Preferred Names Protein Names

sodium channel protein type 8 subunit alpha

  • sodium channel, voltage gated, type VIII, alpha subunit

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-147423 Zandatrigine Inhibitor 99.28% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148792 Relutrigine Inhibitor 99.33% Unkown
HY-RS12545 SCN8A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12546 Scn8a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12547 Scn8a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SCN8A NCBI NCBI:6334