Ugt8 - UDP glycosyltransferase 8 Gene

Also Known as CGalT; Ugt8a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50555

Summary

Enables 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity and UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity. Involved in galactosylceramide biosynthetic process. Located in endoplasmic reticulum. Orthologous to human UGT8 (UDP Glycosyltransferase 8). [provided by Alliance of Genome Resources, Apr 2022]

Ugt8 Products (1)

mRNA Protein Name
NM_019276.3 NP_062149.1 2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acylsphingosine galactosyltransferase activity IDA
IDA: Inferred from direct assay
8713090 RGD
enables UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity IMP
IMP: Inferred from mutant phenotype
7521399 RGD
Biological Process GO Annotation Evidence References Source
involved in galactosylceramide biosynthetic process IDA
IDA: Inferred from direct assay
8713090 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
34449011 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
8713090 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

2-hydroxyacylsphingosine 1-beta-galactosyltransferase

  • UDP galactosyltransferase 8

  • UDP galactosyltransferase 8A

  • UDP-galactose-ceramide galactosyltransferase 8

  • UDP-glucuronosyltransferase 8

  • ceramide UDP-galactosyltransferase

  • cerebroside synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-131703 UGT8-IN-1 Inhibitor 99.94% Unkown
HY-RS15443 UGT8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ugt8 NCBI NCBI:7368