Cacnb1 - calcium voltage-gated channel auxiliary subunit beta 1 Gene

Also Known as CAB1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50688

Summary

Enables several functions, including identical protein binding activity; phosphoprotein binding activity; and protein kinase binding activity. Contributes to voltage-gated Calcium Channel activity. Predicted to be involved in several processes, including cellular response to amyloid-beta; neuromuscular junction development; and regulation of calcium ion transmembrane transport. Predicted to act upstream of or within calcium ion transport and protein targeting to membrane. Part of voltage-gated Calcium Channel complex. Is active in glutamatergic synapse and postsynapse. Orthologous to human CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Cacnb1 Products (1)

mRNA Protein Name
NM_017346.2 NP_059042.2 voltage-dependent L-type calcium channel subunit beta-1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
18776052 RGD
enables phosphoprotein binding IPI
IPI: Inferred from physical interaction
19840220 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16049174 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
19840220 RGD
enables protein kinase binding IDA
IDA: Inferred from direct assay
18205403 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
19840220 RGD
contributes to voltage-gated calcium channel activity IDA
IDA: Inferred from direct assay
16049183 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19996312 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
19996312 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
19996312 RGD
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
19996312 RGD
part of voltage-gated calcium channel complex IDA
IDA: Inferred from direct assay
16049183 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent L-type calcium channel subunit beta-1

  • brain calcium channel beta 1 subunit

  • calcium channel beta 1 subunit

  • calcium channel voltage-dependent subunit beta 1

  • calcium channel, voltage-dependent, beta 1 subunit

Cacnb1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cacnb1 P54283 Cacnb1 Rattus norvegicus P54283
GMS
18776052
Intra
Cacnb1 P54283 Cacnb1 Rattus norvegicus P54283
Density Sedimentation
18776052
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01805 CACNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacnb1 NCBI NCBI:782