HDGFL3 - HDGF like 3 Gene

Also Known as HDGF2; HRP-3; HDGF-2; CGI-142; HDGFRP3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50810

About HDGFL3

Cytogenetic location: 15q25.2 Genomic coordinates (GRCh38): 15:83,112,738-83,207,823 (from NCBI)

This gene has 6 transcripts (splice variants), 189 orthologues and 4 paralogues. Broad expression in testis (RPKM 18.5), brain (RPKM 17.0) and 22 other tissues.

Summary

Predicted to enable double-stranded DNA binding activity; microtubule binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including microtubule polymerization; negative regulation of microtubule depolymerization; and neuron projection development. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HDGFL3 Products (1)

mRNA Protein Name
NM_016073.4 NP_057157.1 hepatoma-derived growth factor-related protein 3

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
10581169 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HDGFL3 Protein Structure

PWWP

PWWP: PWWP domain (9 - 89)

  • 0
  • 100
  • 203 a.a.
Protein Preferred Names Protein Names

hepatoma-derived growth factor-related protein 3

  • hepatoma-derived growth factor 2

Recombinant HDGFL3 Proteins

Cat. No. Product Name Accession Purity
HY-P70942 HDGF2 Protein, Human (HEK293, His) Q9Y3E1 (M1-T203) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06096 HDGFL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris HDGFL3 VGNC VGNC:53179
Mus musculus HDGFL3 MGD MGI:1352760
Macaca mulatta HDGFL3 VGNC VGNC:84346
Rattus norvegicus HDGFL3 RGD RGD:628773
Bos taurus HDGFL3 VGNC VGNC:53939
Others HDGFL3 NCBI