MRTO4 - MRT4 homolog, ribosome maturation factor Gene

Also Known as MRT4; C1orf33; dJ657E11.4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51154

About MRTO4

This gene has 3 transcripts (splice variants) and 227 orthologues. Ubiquitous expression in appendix (RPKM 7.6), lymph node (RPKM 7.5) and 25 other tissues.

Summary

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]

MRTO4 Products (1)

mRNA Protein Name
NM_016183.4 NP_057267.2 mRNA turnover protein 4 homolog

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MRTO4 Protein Structure

Ribosomal_L10

Ribosomal_L10: Ribosomal protein L10 (21 - 120)

  • 0
  • 100
  • 200
  • 239 a.a.
Protein Preferred Names Protein Names

mRNA turnover protein 4 homolog

  • 60S acidic ribosomal protein PO

MRTO4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MRTO4 Q9UKD2 TERF2IP Homo sapiens Q9NYB0
Pull Down
21044950
Intra
MRTO4 Q9UKD2 TERF2IP Homo sapiens Q9NYB0
BiFC
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant MRTO4 Proteins

Cat. No. Product Name Accession Purity
HY-P75465 C1orf33/MRTO4 Protein, Human (His) Q9UKD2 (M1-D239) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Branchiootorenal Syndrome 1

  • Melnick-Fraser Syndrome

  • BOR1

  • Branchiootorenal Dysplasia

  • Branchiootorenal Syndrome 1, With Or Without Cataracts

  • Bor Syndrome 1

  • Branchiootorenal Dysplasia 1

  • Branchio-Oto-Renal Dysplasia 1

  • Branchio-Oto-Renal Syndrome Type 1

  • Branchiootorenal Syndrome, With/Without Cataract, Type 1

  • Branchio-Oto-Renal Syndrome
Shwachman-Diamond Syndrome 1

  • Shwachman-Diamond Syndrome

  • Shwachman Syndrome

  • Shwachman-Bodian-Diamond Syndrome

  • Sds

  • Pancreatic Insufficiency And Bone Marrow Dysfunction

  • Shwachman-Bodian Syndrome

  • SDS1

  • Lipomatosis Of Pancreas, Congenital

  • Congenital Lipomatosis Of Pancreas

  • Shwachman-Diamond Type Metaphyseal Dysplasia

  • Metaphyseal Chondrodysplasia, Shwachman Type

  • Shwachman-Diamond-Oski Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08695 MRTO4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20992 Mrto4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27509 Mrto4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MRTO4 MGD MGI:1917152
Bos taurus MRTO4 VGNC VGNC:31680
Felis catus MRTO4 VGNC VGNC:63629
Canis familiaris MRTO4 VGNC VGNC:84430
Rattus norvegicus MRTO4 RGD RGD:1311709
Others MRTO4 NCBI