RTF2 - replication termination factor 2 Gene

Homo sapiens

Also known as CDAO5; RTFDC1; HSPC164; C20orf43; SHUJUN-3

Gene ID: 51507 | Gene type: protein coding

About RTF2

This gene has 9 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in brain (RPKM 40.3), bone marrow (RPKM 39.0) and 25 other tissues.

Summary

Enables DNA binding activity. Involved in cellular response to hydroxyurea and regulation of DNA stability. Located in replication fork. [provided by Alliance of Genome Resources, Apr 2022]

RTF2 Products(4)

mRNA	Protein	Name
NM_001283035.2	NP_001269964.1	replication termination factor 2 isoform a
NM_001283036.2	NP_001269965.1	replication termination factor 2 isoform c
NM_001283037.2	NP_001269966.1	replication termination factor 2 isoform d
NM_016407.5	NP_057491.2	replication termination factor 2 isoform b

RTF2 Protein Structure

Rtf2

0
100
200
300
336 a.a.

Protein Preferred Names

Protein Names

replication termination factor 2

UPF0549 protein C20orf43

Related Diseases

Diseases

Alias

Amyotrophic Lateral Sclerosis 7

ALS7	Amyotrophic Lateral Sclerosis Type 7

Trichosporonosis

Retinitis Pigmentosa 39

RP39	Retinitis Pigmentosa, Type 39

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12319	RTF2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	RTF2	VGNC	VGNC:45788
Rattus norvegicus	RTF2	RGD	RGD:1311072
Bos taurus	RTF2	VGNC	VGNC:34196
Mus musculus	RTF2	MGD	MGI:1913654
Macaca mulatta	RTF2	VGNC	VGNC:77018