1. Gene
  2. MTFP1 - mitochondrial fission process 1 Gene

MTFP1 - mitochondrial fission process 1 Gene

Homo sapiens

Also known as MTP18; HSPC242

Gene ID: 51537 | Gene type: protein coding

About MTFP1

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:30,425,768-30,429,054 (from NCBI)

This gene has 6 transcripts (splice variants) and 192 orthologues. Ubiquitous expression in duodenum (RPKM 6.4), placenta (RPKM 6.0) and 25 other tissues.

Summary

MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase (see PIK3CA, MIM 171834) signaling pathway that plays a role in cell viability and mitochondrial dynamics (Tondera et al., 2004 [PubMed 15155745]).[supplied by OMIM, Mar 2008]

MTFP1 Products(2)

mRNA Protein Name
NM_001003704.3 NP_001003704.1 mitochondrial fission process protein 1 isoform b
NM_016498.5 NP_057582.2 mitochondrial fission process protein 1 isoform a

MTFP1 Protein Structure

MTP18

MTP18: Mitochondrial 18 KDa protein (MTP18) (19 - 147)

  • 0
  • 100
  • 166 a.a.
Protein Preferred Names Protein Names

mitochondrial fission process protein 1

mitochondrial 18 kDa protein

Related Diseases

Diseases Alias
3-Methylglutaconic Aciduria, Type Iii

Optic Atrophy

3-Methylglutaconic Aciduria Type 3

Costeff Syndrome

Mga3

Costeff Optic Atrophy Syndrome

Optic Atrophy Plus Syndrome

Infantile Optic Atrophy With Chorea And Spastic Paraplegia

3-Methylglutaconic Aciduria Type Iii

Autosomal Recessive Optic Atrophy Plus Syndrome

Autosomal Recessive Optic Atrophy Type 3

Opa3 Defect

MGCA3

Mga, Type Iii

Iraqi Jewish Optic Atrophy Plus

Mga Type Iii

Optic Atrophy, Infantile, With Chorea And Spastic Paraplegia

Iraqi-Jewish 'Optic Atrophy Plus'

Optic Atrophy 3, Autosomal Recessive

Opa3, Autosomal Recessive

Opa3-Related 3-Methylglutaconic Aciduria

Iraqi-Jewish Optic Atrophy Plus

Atrophy Of Optic Disc

3-Alpha Methylglutaconic Aciduria Type Iii

Optic Atrophy 3

Optic Atrophy Infantile With Chorea And Spastic Paraplegia

Autosomal Recessive Opa3

Autosomal Recessive Optic Atrophy 3

3-Methylglutaconic Aciduria 3

3-Alpha-Methylglutaconic Aciduria Type 3

Optic Atrophy 3 Autosomal Recessive

Atrophy, Optic

Atrophy, Optic, Plus Syndrome

Optic Nerve Atrophy

Primary Optic Atrophy

Oa - [Optic Atrophy]

Second Cranial Nerve Atrophy

Second Cranium Nerve Atrophy

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris MTFP1 VGNC VGNC:52952
Mus musculus MTFP1 MGD MGI:1916686
Bos taurus MTFP1 VGNC VGNC:31725
Rattus norvegicus MTFP1 RGD RGD:1359705
Felis catus MTFP1 VGNC VGNC:80455
Others MTFP1 NCBI