Mcrs1 - microspherule protein 1 Gene

Also Known as P78; MSP58; ICP22BP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 51812

Summary

Predicted to enable RNA binding activity and Telomerase Inhibitor activity. Predicted to be involved in histone H4 acetylation; positive regulation of protein localization to nucleolus; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within DNA recombination; DNA repair; and chromatin organization. Predicted to be located in cytoplasm; nucleolus; and nucleoplasm. Predicted to be part of Ino80 complex; MLL1 complex; and NSL complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human MCRS1 (microspherule protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Mcrs1 Products (3)

mRNA Protein Name
NM_001164156.2 NP_001157628.1 microspherule protein 1 isoform 2
NM_001411911.1 NP_001398840.1 microspherule protein 1 isoform 1
NM_016766.4 NP_058046.2 microspherule protein 1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA repair IDA
IDA: Inferred from direct assay
23979016 MGI
involved in positive regulation of telomere maintenance in response to DNA damage IMP
IMP: Inferred from mutant phenotype
23979016 MGI
involved in regulation of DNA repair IDA
IDA: Inferred from direct assay
23979016 MGI
involved in regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
23979016 MGI
involved in telomere maintenance IMP
IMP: Inferred from mutant phenotype
23979016 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microspherule protein 1

  • 58 kDa microspherule protein

  • nucleolar protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-105305 Modimelanotide Ligand 99.06% Unkown
HY-105305A Modimelanotide acetate Ligand / Unkown
HY-RS08248 MCRS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcrs1 NCBI NCBI:10445