Ctdsp2 - CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 Gene

Also Known as OS4; OS-4; SCP2; D10Ertd73e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 52468

Summary

Predicted to enable RNA polymerase II CTD heptapeptide repeat Phosphatase activity. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle and negative regulation of protein phosphorylation. Predicted to be located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; integumental system; respiratory system; and tail. Orthologous to human CTDSP2 (CTD small Phosphatase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ctdsp2 Products (2)

mRNA Protein Name
NM_001113470.1 NP_001106941.1 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform a
NM_146012.2 NP_666124.1 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform b
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
22210897 MGI
acts upstream of or within negative regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
22210897 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

  • nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2) (Protein OS-4)

  • small C-terminal domain phosphatase 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctdsp2 NCBI NCBI:10106