Arhgef25 - Rho guanine nucleotide exchange factor (GEF) 25 Gene

Also Known as GEFT; D10Ertd610e; 2410008H17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 52666

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in axon guidance. Located in myofibril and plasma membrane. Is expressed in several structures, including acoustic ganglion; brain; gut; metanephros; and otocyst. Orthologous to human ARHGEF25 (Rho guanine nucleotide exchange factor 25). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef25 Products (4)

mRNA Protein Name
NM_001166413.1 NP_001159885.1 rho guanine nucleotide exchange factor 25 isoform 2
NM_001358557.1 NP_001345486.1 rho guanine nucleotide exchange factor 25 isoform 3
NM_001358558.1 NP_001345487.1 rho guanine nucleotide exchange factor 25 isoform 4
NM_028027.3 NP_082303.2 rho guanine nucleotide exchange factor 25 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18541910 MGI
Cellular Component GO Annotation Evidence References Source
located in myofibril IDA
IDA: Inferred from direct assay
18541910 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18541910 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 25

  • guanine nucleotide exchange factor GEFT

  • p63RhoGEF

  • rac/Cdc42/Rho exchange factor GEFT

  • rhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00955 ARHGEF25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgef25 NCBI NCBI:115557