Pdlim3 - PDZ and LIM domain 3 Gene

Also Known as ALP; Actn2lp

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53318

Summary

Enables cytoskeletal protein binding activity. A structural constituent of muscle. Acts upstream of or within actin filament organization and heart development. Located in actin Cytoskeleton. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb bud; and retina. Used to study arrhythmogenic right ventricular cardiomyopathy. Orthologous to human PDLIM3 (PDZ and LIM domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Pdlim3 Products (2)

mRNA Protein Name
NM_001374652.2 NP_001361581.1 PDZ and LIM domain protein 3 isoform 1
NM_016798.5 NP_058078.1 PDZ and LIM domain protein 3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytoskeletal protein binding IPI
IPI: Inferred from physical interaction
11329061 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15663004 MGI
enables structural constituent of muscle IDA
IDA: Inferred from direct assay
11238905 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament organization IDA
IDA: Inferred from direct assay
11329061 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
11329061 MGI
NOT acts upstream of or within skeletal muscle tissue development IMP
IMP: Inferred from mutant phenotype
11238905 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IPI
IPI: Inferred from physical interaction
11329061 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PDZ and LIM domain protein 3

  • actinin alpha 2 associated LIM protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10281 PDLIM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdlim3 NCBI NCBI:27295