Syt5 - synaptotagmin V Gene

Also Known as SytV

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53420

Summary

Enables SNARE binding activity; phospholipid binding activity; and protein heterodimerization activity. Involved in regulation of calcium ion-dependent exocytosis. Located in several cellular components, including dense core granule; neuronal cell body; and proximal neuron projection. Is integral component of neuronal dense core vesicle membrane. Is expressed in several structures, including adrenal gland; alimentary system; nervous system; sensory organ; and urinary system. Orthologous to human SYT5 (synaptotagmin 5). [provided by Alliance of Genome Resources, Apr 2022]

Syt5 Products (2)

mRNA Protein Name
NM_001360421.1 NP_001347350.1 synaptotagmin-5
NM_001360422.1 NP_001347351.1 synaptotagmin-5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SNARE binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables calcium-dependent phospholipid binding IDA
IDA: Inferred from direct assay
8626542 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
12860971 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
10531344 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
12860971 MGI
Cellular Component GO Annotation Evidence References Source
located in dense core granule IDA
IDA: Inferred from direct assay
14622145 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
15197251 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
15197251 MGI
is active in neuronal dense core vesicle membrane IDA
IDA: Inferred from direct assay
12006594 MGI
is active in neuronal dense core vesicle membrane IEP
IEP: Inferred from expression pattern
12006594 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15197251 MGI
located in proximal neuron projection IDA
IDA: Inferred from direct assay
15197251 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-5

  • synaptotagmin IX

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14117 SYT5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syt5 NCBI NCBI:6861