2. Gene
  3. Sec61a1 - Sec61 alpha 1 subunit (S. cerevisiae) Gene

Sec61a1 - Sec61 alpha 1 subunit (S. cerevisiae) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sec61a

Gene ID: 53421 | Gene type: protein coding

About Sec61a1

Summary

Enables ribosome binding activity and transmembrane transporter activity. Involved in pronephric nephron development. Predicted to be located in endoplasmic reticulum membrane and rough endoplasmic reticulum. Predicted to be part of Sec61 translocon complex. Is expressed in cerebral cortex; jaw; skeleton; and vibrissa. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human SEC61A1 (Sec61 translocon subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Sec61a1 Products(1)

mRNA Protein Name
NM_016906.4 NP_058602.1 protein transport protein Sec61 subunit alpha isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ribosome binding IDA
IDA: Inferred from direct assay
16705175 MGI
enables transmembrane transporter activity EXP
EXP: Inferred from Experiment
14508489 MGI
Biological Process GO Annotation Evidence Reference Source
involved in pronephric nephron development IMP
IMP: Inferred from mutant phenotype
27392076 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein transport protein Sec61 subunit alpha isoform 1

SEC61, alpha subunit

protein transport protein Sec61 subunit alpha

sec61 alpha-1

transport protein sec61 alpha subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139615 Sec61-IN-1 Inhibitor 99.70% Unkown
HY-RS12621 SEC61A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sec61a1 NCBI NCBI:29927