Ddx20 - DEAD box helicase 20 Gene

Mus musculus

Also known as dp103; GEMIN3

Gene ID: 53975 | Gene type: protein coding

About Ddx20

Summary

Enables histone deacetylase binding activity and protein-macromolecule adaptor activity. Involved in positive regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II; oogenesis; and regulation of steroid biosynthetic process. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including branchial arch; genitourinary system; liver; lung; and spleen. Orthologous to human DDX20 (DEAD-box helicase 20). [provided by Alliance of Genome Resources, Apr 2022]

Ddx20 Products(1)

mRNA	Protein	Name
NM_017397.3	NP_059093.3	probable ATP-dependent RNA helicase DDX20

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables histone deacetylase binding	IPI IPI: Inferred from physical interaction	12007404	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12007404	MGI
enables protein-macromolecule adaptor activity	IDA IDA: Inferred from direct assay	12007404	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	12007404	MGI
acts upstream of or within oogenesis	IMP IMP: Inferred from mutant phenotype	18258677	MGI
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	16153597	MGI
acts upstream of or within regulation of steroid biosynthetic process	IMP IMP: Inferred from mutant phenotype	18258677	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of RNA polymerase II transcription repressor complex	IDA IDA: Inferred from direct assay	12007404	MGI
part of transcription repressor complex	IDA IDA: Inferred from direct assay	12007404	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

probable ATP-dependent RNA helicase DDX20

DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	DEAD box protein 20
DEAD box protein DP 103	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20
ROSF-1	component of gems 3
gemin-3	regulator of steroidogenic factor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03636	DDX20 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ddx20	NCBI	NCBI:11218

Name
Email *

	Sorry, but the email address you supplied was invalid.