Ddx20 - DEAD box helicase 20 Gene

Also Known as dp103; GEMIN3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53975

Summary

Enables histone deacetylase binding activity and protein-macromolecule adaptor activity. Involved in positive regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II; oogenesis; and regulation of steroid biosynthetic process. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including branchial arch; genitourinary system; liver; lung; and spleen. Orthologous to human DDX20 (DEAD-box helicase 20). [provided by Alliance of Genome Resources, Apr 2022]

Ddx20 Products (1)

mRNA Protein Name
NM_017397.3 NP_059093.3 probable ATP-dependent RNA helicase DDX20

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone deacetylase binding IPI
IPI: Inferred from physical interaction
12007404 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12007404 MGI
enables protein-macromolecule adaptor activity IDA
IDA: Inferred from direct assay
12007404 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12007404 MGI
acts upstream of or within oogenesis IMP
IMP: Inferred from mutant phenotype
18258677 MGI
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16153597 MGI
acts upstream of or within regulation of steroid biosynthetic process IMP
IMP: Inferred from mutant phenotype
18258677 MGI
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase II transcription repressor complex IDA
IDA: Inferred from direct assay
12007404 MGI
part of transcription repressor complex IDA
IDA: Inferred from direct assay
12007404 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable ATP-dependent RNA helicase DDX20

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 20

  • DEAD box protein 20

  • DEAD box protein DP 103

  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20

  • ROSF-1

  • component of gems 3

  • gemin-3

  • regulator of steroidogenic factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03636 DDX20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddx20 NCBI NCBI:11218