Pdlim1 - PDZ and LIM domain 1 Gene

Also Known as CLP36

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54133

Summary

Enables actin binding activity. Involved in several processes, including actin Cytoskeleton organization; fibroblast migration; and maintenance of cell polarity. Located in Z disc and stress fiber. Orthologous to human PDLIM1 (PDZ and LIM domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdlim1 Products (1)

mRNA Protein Name
NM_017365.2 NP_059061.1 PDZ and LIM domain protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
22659164 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
22659164 RGD
Biological Process GO Annotation Evidence References Source
involved in actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
22659164 RGD
involved in establishment or maintenance of actin cytoskeleton polarity IMP
IMP: Inferred from mutant phenotype
22659164 RGD
involved in fibroblast migration IMP
IMP: Inferred from mutant phenotype
22659164 RGD
involved in maintenance of cell polarity IMP
IMP: Inferred from mutant phenotype
22659164 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
8522188 RGD
involved in stress fiber assembly IMP
IMP: Inferred from mutant phenotype
22659164 RGD
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
22659164 RGD
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
22659164 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
22659164 RGD
located in stress fiber IDA
IDA: Inferred from direct assay
22659164 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PDZ and LIM domain protein 1

  • C-terminal LIM domain protein 1

  • LIM domain protein CLP-36

  • LIM protein

  • elfin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10279 PDLIM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdlim1 NCBI NCBI:9124