Pdlim1 - PDZ and LIM domain 1 Gene

Rattus norvegicus

Also known as CLP36

Gene ID: 54133 | Gene type: protein coding

About Pdlim1

Summary

Enables actin binding activity. Involved in several processes, including actin Cytoskeleton organization; fibroblast migration; and maintenance of cell polarity. Located in Z disc and stress fiber. Orthologous to human PDLIM1 (PDZ and LIM domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdlim1 Products(1)

mRNA	Protein	Name
NM_017365.2	NP_059061.1	PDZ and LIM domain protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables actin binding	IDA IDA: Inferred from direct assay	22659164	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	22659164	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	22659164	RGD
involved in establishment or maintenance of actin cytoskeleton polarity	IMP IMP: Inferred from mutant phenotype	22659164	RGD
involved in fibroblast migration	IMP IMP: Inferred from mutant phenotype	22659164	RGD
involved in maintenance of cell polarity	IMP IMP: Inferred from mutant phenotype	22659164	RGD
involved in response to hypoxia	IEP IEP: Inferred from expression pattern	8522188	RGD
involved in stress fiber assembly	IMP IMP: Inferred from mutant phenotype	22659164	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in Z disc	IDA IDA: Inferred from direct assay	22659164	RGD
located in actin cytoskeleton	IDA IDA: Inferred from direct assay	22659164	RGD
located in cytoplasm	IDA IDA: Inferred from direct assay	22659164	RGD
located in stress fiber	IDA IDA: Inferred from direct assay	22659164	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

PDZ and LIM domain protein 1

C-terminal LIM domain protein 1	LIM domain protein CLP-36
LIM protein	elfin

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10279	PDLIM1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pdlim1	NCBI	NCBI:9124

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