2. Gene
  3. Pabpn1 - poly(A) binding protein, nuclear 1 Gene

Pabpn1 - poly(A) binding protein, nuclear 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PAB2; Pabp3; mPABII

Gene ID: 54196 | Gene type: protein coding

About Pabpn1

Summary

Enables RNA polymerase binding activity. Involved in MAPK cascade; cellular response to lipopolysaccharide; and positive regulation of polynucleotide adenylyltransferase activity. Located in nucleus. Part of ribonucleoprotein complex. Is expressed in central nervous system; sensory organ; and thymus. Used to study oculopharyngeal muscular dystrophy. Human ortholog(s) of this gene implicated in oculopharyngeal muscular dystrophy. Orthologous to human PABPN1 (poly(A) binding protein nuclear 1). [provided by Alliance of Genome Resources, Apr 2022]

Pabpn1 Products(1)

mRNA Protein Name
NM_019402.2 NP_062275.1 polyadenylate-binding protein 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RNA polymerase binding IDA
IDA: Inferred from direct assay
22844456 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22844456 MGI
Biological Process GO Annotation Evidence Reference Source
involved in MAPK cascade IMP
IMP: Inferred from mutant phenotype
22844456 MGI
involved in cellular response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
22844456 MGI
involved in positive regulation of polynucleotide adenylyltransferase activity IMP
IMP: Inferred from mutant phenotype
22844456 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
22844456 MGI
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
22844456 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyadenylate-binding protein 2

PABII

PABP-2

nuclear poly(A)-binding protein 1

poly(A) binding protein II

poly(A)-binding protein 2

polyadenylate-binding nuclear protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09952 PABPN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pabpn1 NCBI NCBI:8106