Cr1l - complement C3b/C4b receptor 1 like Gene

Also Known as Cr1; Crry

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54243

Summary

This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 Amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Cr1l Products (2)

mRNA Protein Name
NM_001005265.1 NP_001005265.1 complement component receptor 1-like protein isoform 3 precursor
NM_019301.2 NP_062174.1 complement component receptor 1-like protein isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of complement activation IMP
IMP: Inferred from mutant phenotype
11861390 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement component receptor 1-like protein

  • 5I2 antigen

  • Complement receptor related protein

  • antigen 5I2

  • complement component (3b/4b) receptor 1-like

  • complement receptor type 1

  • complement regulatory protein Crry

  • complement regulatory protein Crry-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03132 CR1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cr1l NCBI NCBI:1379