2. Gene
  3. Cr1l - complement C3b/C4b receptor 1 like Gene

Cr1l - complement C3b/C4b receptor 1 like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cr1; Crry

Gene ID: 54243 | Gene type: protein coding

About Cr1l

Summary

This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 Amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Cr1l Products(2)

mRNA Protein Name
NM_001005265.1 NP_001005265.1 complement component receptor 1-like protein isoform 3 precursor
NM_019301.2 NP_062174.1 complement component receptor 1-like protein isoform 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of complement activation IMP
IMP: Inferred from mutant phenotype
11861390 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement component receptor 1-like protein

5I2 antigen

Complement receptor related protein

antigen 5I2

complement component (3b/4b) receptor 1-like

complement receptor type 1

complement regulatory protein Crry

complement regulatory protein Crry-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03132 CR1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cr1l NCBI NCBI:1379