Slc23a2 - solute carrier family 23 (nucleobase transporters), member 2 Gene

Mus musculus

Also known as NBTL1; SVCT2; YSPL2; YSPL3; Slc23a1; mKIAA0238

Gene ID: 54338 | Gene type: protein coding

About Slc23a2

Summary

Enables L-ascorbate:sodium symporter activity and L-ascorbic acid transmembrane transporter activity. Involved in L-ascorbic acid transmembrane transport. Located in basal plasma membrane and cytoplasm. Is expressed in adrenal gland; central nervous system; metanephros; and retina. Orthologous to human SLC23A2 (solute carrier family 23 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc23a2 Products(3)

mRNA	Protein	Name
NM_001355430.1	NP_001342359.1	solute carrier family 23 member 2 isoform a
NM_001355431.1	NP_001342360.1	solute carrier family 23 member 2 isoform b
NM_018824.2	NP_061294.2	solute carrier family 23 member 2 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables L-ascorbate:sodium symporter activity	IMP IMP: Inferred from mutant phenotype	11984597	MGI
enables L-ascorbic acid transmembrane transporter activity	IDA IDA: Inferred from direct assay	18668520	MGI
enables L-ascorbic acid transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	15333707	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-ascorbic acid transmembrane transport	IDA IDA: Inferred from direct assay	18668520	MGI
involved in L-ascorbic acid transmembrane transport	IMP IMP: Inferred from mutant phenotype	15333707	MGI
acts upstream of or within blood circulation	IMP IMP: Inferred from mutant phenotype	33544780	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basal plasma membrane	IDA IDA: Inferred from direct assay	18668520	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	18668520	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

solute carrier family 23 member 2

Na(+)/L-ascorbic acid transporter 2	SVCT-2
mSVCT2	sodium-dependent vitamin C transporter 2
solute carrier family 23 (nucleobase transporters), member 1	yolk sac permease-like molecule 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13081	SLC23A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13082	SLC23A2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc23a2	NCBI	NCBI:9962

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