Scfd1 - sec1 family domain containing 1 Gene

Rattus norvegicus

Also known as Sly1; RA410; rSly1

Gene ID: 54350 | Gene type: protein coding

About Scfd1

Summary

Enables protein N-terminus binding activity and syntaxin binding activity. Involved in Golgi vesicle transport; regulation of ER to Golgi vesicle-mediated transport; and response to hypoxia. Located in Golgi-associated vesicle and plasma membrane. Orthologous to human SCFD1 (sec1 family domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Scfd1 Products(1)

mRNA	Protein	Name
NM_019364.1	NP_062237.1	sec1 family domain-containing protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11879635	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	19536132	RGD
enables syntaxin binding	IDA IDA: Inferred from direct assay	15670607	RGD
enables syntaxin binding	IPI IPI: Inferred from physical interaction	10930465	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in post-Golgi vesicle-mediated transport	IDA IDA: Inferred from direct assay	9195952	RGD
involved in regulation of ER to Golgi vesicle-mediated transport	IMP IMP: Inferred from mutant phenotype	14565970	RGD
involved in response to hypoxia	IEP IEP: Inferred from expression pattern	9195952	RGD
involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IMP IMP: Inferred from mutant phenotype	19536132	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in Golgi-associated vesicle	IDA IDA: Inferred from direct assay	9195952	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sec1 family domain-containing protein 1

SLY1 homolog	sly1p
syntaxin-binding protein 1-like 2	vesicle transport-related protein Ra410

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12499	SCFD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Scfd1	NCBI	NCBI:23256

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