2. Gene
  3. Iqgap2 - IQ motif containing GTPase activating protein 2 Gene

Iqgap2 - IQ motif containing GTPase activating protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A630053O10; 4933417J23Rik

Gene ID: 544963 | Gene type: protein coding

About Iqgap2

Summary

Predicted to enable several functions, including Arp2/3 complex binding activity; GTPase activator activity; and Calmodulin binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; regulation of actin Cytoskeleton reorganization; and thrombin-activated receptor signaling pathway. Located in microvillus. Is expressed in several structures, including alimentary system; axial skeleton; central nervous system; genitourinary system; and liver. Used to study hepatocellular carcinoma. Orthologous to human IQGAP2 (IQ motif containing GTPase activating protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Iqgap2 Products(1)

mRNA Protein Name
NM_027711.1 NP_081987.1 ras GTPase-activating-like protein IQGAP2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in microvillus IDA
IDA: Inferred from direct assay
18604197 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras GTPase-activating-like protein IQGAP2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06886 IQGAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Iqgap2 NCBI NCBI:10788