L1TD1 - LINE1 type transposase domain containing 1 Gene
Also Known as ECAT11
Species: Homo sapiens
About L1TD1
This gene has 1 transcript (splice variant) and 1094 orthologues. Biased expression in placenta (RPKM 6.2), testis (RPKM 4.7) and 4 other tissues.
Summary
Predicted to enable single-stranded RNA binding activity. Predicted to be involved in transposition, RNA-mediated. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
L1TD1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001164835.2 | NP_001158307.1 | LINE-1 type transposase domain-containing protein 1 |
| NM_019079.5 | NP_061952.3 | LINE-1 type transposase domain-containing protein 1 |
L1TD1 Protein Structure
Transposase_22: L1 transposable element RBD-like domain (216 - 322)
Transposase_22: L1 transposable element RBD-like domain (529 - 862)
- 0
- 200
- 400
- 600
- 800
- 865 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
LINE-1 type transposase domain-containing protein 1 |
|
L1TD1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
L1TD1 | Q5T7N2 | HNRNPA2B1 | Homo sapiens | P22626 | 30021884 | |
|
Intra
|
L1TD1 | Q5T7N2 | HNRNPA2B1 | Homo sapiens | P22626 | 25702638 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Testis Seminoma |
|
|
| Inflammatory Bowel Disease 7 |
|
|
| Spastic Paraplegia 16, X-Linked |
|
|
| Spastic Paraplegia 12, Autosomal Dominant |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Felis catus | L1TD1 | VGNC | VGNC:107571 |
| Mus musculus | L1TD1 | MGD | MGI:3578435 |
| Macaca mulatta | L1TD1 | VGNC | VGNC:74125 |
| Rattus norvegicus | L1TD1 | RGD | RGD:1595093 |
| Others | L1TD1 | NCBI |