FEZF2 - FEZ family zinc finger 2 Gene

Also Known as FEZ; TOF; FEZL; FKSG36; ZFP312; ZNF312

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 55079

About FEZF2

Cytogenetic location: 3p14.2 Genomic coordinates (GRCh38): 3:62,369,681-62,373,550 (from NCBI)

This gene has 3 transcripts (splice variants), 193 orthologues and 28 paralogues. Restricted expression toward brain (RPKM 4.1).

Summary

Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and regulation of neuron differentiation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FEZF2 Products (1)

mRNA	Protein	Name
NM_018008.4	NP_060478.3	fez family zinc finger protein 2

FEZF2 Protein Structure

zf-H2C2_2

zf-C2H2

zf-H2C2_2

zf-C2H2

0
100
200
300
400
459 a.a.

Protein Preferred Names	Protein Names
fez family zinc finger protein 2	forebrain embryonic zinc finger-like protein 2

Related Diseases

Diseases	Alias
Uterine Inversion	Inversion Of Uterus During Delivery
Myopathy, Myosin Storage, Autosomal Dominant	MSMA Myopathy, Hyaline Body, Autosomal Dominant Myopathy With Lysis Of Type I Myofibrils Autosomal Dominant Hyaline Body Myopathy Hyaline Body Myopathy Autosomal Dominant
Thymic Dysplasia
Partial Fetal Alcohol Syndrome
Autoimmune Polyendocrine Syndrome Type 1	Whitaker Syndrome Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Autoimmune Polyglandular Syndrome I Polyglandular Type I Autoimmune Syndrome
Autoimmune Polyendocrine Syndrome	Autoimmune Polyendocrinopathy Autoimmune Polyglandular Failure Autoimmune Polyglandular Syndrome Polyendocrinopathies, Autoimmune Lloyd'S Syndrome Aps Polyendocrinopathies Autoimmune Polyendocrine Autoimmunity Syndrome Lloyd Syndrome Polyglandular Autoimmune Deficiency Progressive Pluriglandular Insufficiency Pluriglandular Autoimmune Atrophy Pluriglandular Autoimmune Syndrome Thyroid-Adrenocortical Insufficiency Syndrome
Congenital Nervous System Abnormality	Congenital Neurologic Anomaly Congenital Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04873	FEZF2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FEZF2	VGNC	VGNC:28960
Mus musculus	FEZF2	MGD	MGI:1859823
Felis catus	FEZF2	VGNC	VGNC:62235
Canis familiaris	FEZF2	VGNC	VGNC:40829
Rattus norvegicus	FEZF2	RGD	RGD:1311068
Macaca mulatta	FEZF2	VGNC	VGNC:72485