DEPDC1 - DEP domain containing 1 Gene

Homo sapiens

Also known as DEP.8; SDP35; DEPDC1A; DEPDC1-V2

Gene ID: 55635 | Gene type: protein coding

About DEPDC1

Cytogenetic location: 1p31.3 Genomic coordinates (GRCh38): 1:68,474,152-68,497,082 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues and 3 paralogues. Biased expression in testis (RPKM 5.4), lymph node (RPKM 3.0) and 13 other tissues.

Summary

Predicted to enable GTPase activator activity. Involved in negative regulation of transcription, DNA-templated. Located in nucleus. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2022]

DEPDC1 Products(2)

mRNA	Protein	Name
NM_001114120.3	NP_001107592.1	DEP domain-containing protein 1A isoform a
NM_017779.6	NP_060249.2	DEP domain-containing protein 1A isoform b

DEPDC1 Protein Structure

DEP

0
200
400
600
811 a.a.

Protein Preferred Names

Protein Names

DEP domain-containing protein 1A

cell cycle control protein SDP35

Related Diseases

Diseases

Alias

Bladder Cancer

Urinary Bladder Cancer	Bladder Carcinoma
Urinary Bladder Carcinoma	Bladder Neoplasm
Bladder Tumor	Cancer, Bladder
Malignant Neoplasm Of Urinary Bladder	Carcinoma Of Bladder
Bladder Cancer, Somatic	Tumor Of The Bladder
Carcinoma Of Urinary Bladder	Bladder Carcinoma Urinary
Cancer Of The Urinary Bladder	Cancer, Urinary Bladder
Malignant Bladder Neoplasm	Malignant Bladder Tumor
Neoplasm Of The Bladder	Neoplasm Of The Urinary Bladder
Tumor Of The Urinary Bladder	Urinary Bladder Neoplasm
BLC	Urothelial Carcinoma Of The Bladder
Bladder Tumors	Urinary Bladder Neoplasms
Bladder Cancer Nos	Vesical Cancer Nos
Malignant Neoplasm Of Bladder, Part Unspecified	Malignant Tumour Of Urinary Bladder
Primary Malignant Neoplasm Of Bladder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03693	DEPDC1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS03694	DEPDC1B Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	DEPDC1	VGNC	VGNC:39896
Rattus norvegicus	DEPDC1	RGD	RGD:1306987
Bos taurus	DEPDC1	VGNC	VGNC:55165
Mus musculus	DEPDC1	MGD	MGI:1923381
Macaca mulatta	DEPDC1	VGNC	VGNC:99886
Felis catus	DEPDC1	VGNC	VGNC:61443

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