DEPDC1 Antibody
(Synonyms: DEPDC1)DEPDC1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DEPDC1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse
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Formulation:
Supplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1000 |
Product Details
DEPDC1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DEPDC1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 93 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 93 kDa
Fusion protein of human DEPDC1.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DEPDC1 may be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expressed in testis. Up-regulated in bladder cancer cells (at protein level). -
Isoforms & Post-Translational Modification
DEPDC1 has 2 isoforms, Q5TB30-5: amino acid length is 811, molecular weight is 92960 Da (predicted); Q5TB30-2: amino acid length is 527, molecular weight is 61493 Da (predicted).
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Subunit
Isoform 2 and isoform 5 can form homodimers and heterodimers.
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SwissProt ID
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Synonyms
DEPDC1
Documentation
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