PLGRKT - plasminogen receptor with a C-terminal lysine Gene

Also Known as AD025; MDS030; C9orf46; PLG-RKT; Plg-R(KT)

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55848

About PLGRKT

Cytogenetic location: 9p24.1 Genomic coordinates (GRCh38): 9:5,357,971-5,438,377 (from NCBI)

This gene has 4 transcripts (splice variants) and 186 orthologues. Ubiquitous expression in colon (RPKM 12.9), duodenum (RPKM 11.8) and 24 other tissues.

Summary

Predicted to be involved in positive regulation of plasminogen activation. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PLGRKT Products (1)

mRNA Protein Name
NM_018465.4 NP_060935.2 plasminogen receptor (KT)

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLGRKT Protein Structure

DUF2368

DUF2368: Uncharacterised conserved protein (DUF2368) (1 - 135)

  • 0
  • 100
  • 147 a.a.
Protein Preferred Names Protein Names

plasminogen receptor (KT)

  • 5033414D02Rik

PLGRKT Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PLGRKT Q9HBL7 EEF1G Homo sapiens P26641-2
Y2H Prey Pooling
25416956
Intra
PLGRKT Q9HBL7 EEF1G Homo sapiens P26641-2
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Plasminogen Deficiency, Type I

  • Hypoplasminogenemia

  • Dysplasminogenemia

  • Plasminogen Deficiency Type I

  • Congenital Plasminogen Deficiency

  • Ligneous Conjunctivitis

  • Type 1 Plasminogen Deficiency

  • Plasminogen Deficiency Type 1

  • Plasminogen Deficiency

  • PLGD

  • Plasminogen Deficiency Type Ii

  • Deficiency, Plasminogen, Type I
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10705 PLGRKT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PLGRKT VGNC VGNC:33028
Macaca mulatta PLGRKT VGNC VGNC:76098
Mus musculus PLGRKT MGD MGI:1915009
Canis familiaris PLGRKT VGNC VGNC:44689
Felis catus PLGRKT VGNC VGNC:102964
Rattus norvegicus PLGRKT RGD RGD:1306839
Others PLGRKT NCBI